The HPE ProLiant DL380 Gen11 Rack Server is a versatile 2U platform designed for performance and scalability. Powered by Intel Xeon Scalable processors with DDR5 and PCIe Gen5, it provides flexible compute and storage for virtualisation, databases, and hybrid workloads.
Guide price: £2,290.86 – £4,521.44Price range: £2,290.86 through £4,521.44 Ex. VAT
IT teams face increasing pressure to run more workloads, deliver faster application performance, and maintain secure infrastructure while managing operational complexity and infrastructure costs.
The HPE ProLiant DL380 Gen11 is a versatile 2U rack server designed to support a wide range of enterprise workloads. Powered by 4th and 5th Generation Intel Xeon Scalable processors with up to 60 cores per CPU, the platform supports high-capacity DDR5 memory, advanced security features, and flexible storage configurations to accelerate virtualisation, databases, analytics, and application platforms.
The DL380 Gen11 combines powerful compute performance with greater expansion capability than compact 1U servers. Support for PCIe Gen5 connectivity, NVMe storage, and flexible drive configurations allows networking, accelerator hardware, and storage devices to operate at full bandwidth without bottlenecks. Organisations that require four-socket scale-up for larger in-memory and consolidation workloads may also consider the HPE ProLiant DL560 Gen11 Mission-Critical Server, for supporting bigger memory footprints and higher VM density in one server tier.
By consolidating multiple workloads onto fewer high-performance systems, the DL380 Gen11 helps reduce infrastructure complexity and operational overhead. Integrated HPE Integrated Lights-Out (iLO) 6 enables secure remote management, allowing organisations to maintain reliable operations while scaling infrastructure as demand grows.
Our specialists can help assess your infrastructure requirements and design HPE ProLiant DL380 Gen11 platforms aligned with your workload and performance objectives.
The HPE ProLiant DL380 Gen11 Rack Server delivers versatile enterprise compute designed for virtualisation, databases, and enterprise applications requiring scalable performance and flexible storage configurations.
Intel Xeon Scalable Processor Support
Supports 4th Gen Intel Xeon Scalable processors for demanding enterprise workloads.
Dual-Socket 2U Server Design
Provides increased expansion capacity and flexible storage configurations.
Flexible Storage Configurations
Supports LFF and SFF drive configurations depending on server model.
High-Speed PCIe Gen5 Expansion
Supports next-generation networking and accelerator hardware.
HPE Silicon Root of Trust
Provides hardware-level firmware security.
HPE Integrated Lights-Out (iLO) 6
Supports remote server management and monitoring.
Automated Infrastructure Analytics
Supports proactive monitoring and performance optimisation.
Whether supporting enterprise applications or building scalable virtualisation platforms, we help design HPE ProLiant DL380 Gen11 environments that deliver reliable performance.
Full specifications for this model are listed below.
| Product Family | HPE ProLiant |
|---|---|
| Product Series | DL380 |
| Platform Generation | |
| Deployment | Data Centre |
| Primary Use Case | Enterprise Applications |
| Product Tier | Flagship |
| Chassis Type | |
| Form Factor | |
| CPU Vendor | |
| Processor Platform | |
| CPU Architecture Class | |
| Maximum CPUs Supported | |
| Memory Type | |
| Maximum Memory Capacity | |
| Memory Slots | |
| Maximum Memory Speed (MT/s) | |
| Drive Bay Configuration | |
| Maximum Storage Capacity | |
| NVMe Drive Support | |
| Maximum GPUs Supported | |
| PCI Express Slots | |
| PCIe Generation | |
| Embedded Network Ports | |
| Maximum Network Speed | |
| OCP / Network Expansion | |
| Maximum Power Supply (W) | |
| Power Redundancy | Hot-swappable PSUs |
| Remote Management |
Our specialists are here to help assess compatibility, compare suitable alternatives, or talk through your configuration needs before committing to a solution.
Contact us today for a no-obligation chat.
The HPE ProLiant DL380 Gen11 Rack Server is designed for organisations that need a versatile 2U dual-socket platform for mainstream enterprise infrastructure. It is best suited to environments where balanced compute, broader storage choice, and dependable expansion matter more than the 1U density of the DL360 or the single-socket efficiency of the DL325.
Large virtual server estates often need a host platform that balances core count, memory capacity, and drive flexibility across mixed workloads. The DL380 Gen11 fits these environments where one server family is expected to support broad virtualisation use without narrowing the design to a specialist role.
Production environments with larger local data requirements often need more drive flexibility than a denser 1U server can offer. The DL380 Gen11 works well where 8 LFF, 12 LFF, 8 SFF, or 24 SFF chassis options are used to align the server to capacity-led, balanced, or performance-led application storage needs.
ERP platforms, operational databases, and line-of-business systems often need a general-purpose server that can scale cleanly without becoming overly specialised. The DL380 Gen11 suits these deployments where application breadth matters as much as raw compute performance.
User-facing platforms such as VDI, session-based workloads, and shared enterprise services often benefit from a 2U server that balances memory, PCIe expansion, and storage options. The DL380 Gen11 is a practical fit where infrastructure density must stay flexible rather than fixed to one workload type.
Many organisations standardise on the DL380 family as their default rack server for mixed production estates. The DL380 Gen11 is well matched to that role where one adaptable 2U platform needs to support virtualisation, applications, and infrastructure services across the same server estate.
Our team can help design and deploy HPE ProLiant DL380 Gen11 infrastructure for virtualisation, business applications, and versatile 2U enterprise compute environments.
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Below you’ll find alternative models, suitable software and services that pair with this solution – helping you to avoid compatibility issues, reduce support overhead and deploy with confidence.
Not all deployments fit standard configurations. If you’re weighing up options or want a second opinion on your setup, our team is here to help with honest, straightforward advice backed by decades of vendor knowledge.




Not sure which model is right for your environment? Our specialists can help you select the right platform for your infrastructure requirements.