HPE ProLiant DL385 Gen11 Rack Server

The HPE ProLiant DL385 Gen11 Rack Server is a powerful 2U platform powered by AMD EPYC processors. Designed for virtualisation, AI, and data-intensive workloads, it delivers high core density, PCIe Gen5 expansion, and DDR5 memory for scalable enterprise infrastructure.

HPE ProLiant DL385 Gen11 Key Platform Specifications

  • Primary Use Case: High-Performance Compute
  • Processor Platform: EPYC 4th Gen
  • Maximum CPUs Supported: 2
  • Maximum Memory Capacity: 6 TB
  • Memory Slots: 24
  • Maximum GPUs Supported: 4

Guide price: Price range: £2,731.82 through £6,500.00 Ex. VAT

SKU DL385-Gen11 Categories , , Brand:

HPE ProLiant DL385 Gen11 Overview

Virtualised environments and modern application platforms require compute infrastructure capable of delivering strong performance while maintaining efficiency and scalability.

High-Core AMD Compute for Enterprise Workloads

The HPE ProLiant DL385 Gen11 is a dual-socket 2U rack server powered by 4th Generation AMD EPYC processors with high core density and support for large memory configurations. The platform supports DDR5 memory, PCIe Gen5 connectivity, and high-speed NVMe storage for demanding application workloads. Support for modern memory, storage, and I/O keeps application, database, and virtualisation workloads responsive as utilisation rises and data movement increases across the platform.

Flexible Infrastructure for Data-Intensive Applications

Extensive I/O expansion and storage flexibility allow the DL385 Gen11 to support workloads such as virtualisation, analytics, and large-scale data processing. High-density compute and platform bandwidth give infrastructure teams more room to consolidate services, standardise deployments, and avoid creating additional server silos as requirements grow. Organisations that require larger scale-up workloads than a 2-socket platform is designed for may also consider the HPE ProLiant DL560 Gen11 Mission-Critical Server, for supporting bigger memory footprints and consolidation ratios.

Supporting Workload Consolidation and Infrastructure Efficiency

High core density and modern platform bandwidth enable organisations to consolidate workloads onto fewer servers while maintaining strong application performance.

Our specialists can help design and deploy HPE ProLiant DL385 Gen11 platforms aligned with virtualised and data-intensive infrastructure environments. It also gives IT teams a more practical platform for planned growth without adding unnecessary management overhead.

HPE ProLiant DL385 Gen11 Key Features​

The HPE ProLiant Compute DL385 Gen11 is a 2U dual-socket AMD server designed for high-performance workloads, delivering scalable compute, large memory capacity, and flexible storage.

Scalable Dual-Socket Compute Performance

AMD EPYC Processor Platform
Supports dual AMD EPYC processors for compute-intensive workloads.

Large Memory Capacity
Supports high-capacity DDR5 memory for demanding applications.

Flexible Storage Options
Supports multiple drive configurations including NVMe.

PCIe Expansion
Enables high-speed connectivity for networking and storage.

Enterprise Management and Security

HPE iLO Management
Provides remote management and monitoring.

Silicon Root of Trust
Ensures system security at the firmware level.

Automation and Monitoring
Supports HPE management platforms for operational control.

Speak to an HPE Compute Specialist

Whether supporting virtualisation or high-performance applications, we help design HPE ProLiant DL385 Gen11 environments for scalable compute performance.

HPE ProLiant DL385 Gen11 Technical Specifications

Full specifications for this model are listed below.

Additional information

Product Family

HPE ProLiant

Product Series

DL385

Platform Generation

Deployment

Data Centre

Primary Use Case

High-Performance Compute

Product Tier

Standard

Chassis Type

Form Factor

CPU Vendor

Processor Platform

CPU Architecture Class

Maximum CPUs Supported

Memory Type

Maximum Memory Capacity

Memory Slots

Maximum Memory Speed (MT/s)

Drive Bay Configuration

Maximum Storage Capacity

NVMe Drive Support

Maximum GPUs Supported

PCI Express Slots

PCIe Generation

Embedded Network Ports

Maximum Network Speed

OCP / Network Expansion

Maximum Power Supply (W)

Power Redundancy

Hot-swappable PSUs

Remote Management

Evaluating whether this is the right fit for your environment?

Our specialists are here to help assess compatibility, compare suitable alternatives, or talk through your configuration needs before committing to a solution.

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HPE ProLiant DL385 Gen11 Deployment Scenarios

 

The HPE ProLiant DL385 Gen11 Rack Server is designed for organisations that need a 2U dual-socket AMD platform for higher core density, larger memory scale, and broader expansion than a compact 1U host. It is best suited to workloads that need more storage and PCIe headroom than the DL325 Gen11, while remaining a mainstream enterprise server rather than moving into the specialised AI role of the DL380a family.

Dense Virtualisation Estates

The DL385 Gen11 is a strong fit for larger virtualisation environments where host density, memory capacity, and local storage flexibility all matter at the same time. It works well where a 2U chassis gives more room for mixed VM growth than a smaller single-socket server.

Software-Defined Infrastructure

Software-defined storage and compute platforms often need strong processor scale, fast PCIe Gen5 I/O, and flexible local media layouts in one chassis. The DL385 Gen11 suits these deployments because it combines dual-socket AMD performance with broader expansion than the DL325.

Storage-Rich Application Platforms

Application estates that need more local storage choice can use 8 SFF, 8 LFF, 12 EDSFF, or 48 SFF variants to match the workload. The DL385 Gen11 is well matched to environments where local media layout is part of the platform decision rather than a fixed compromise.

Accelerated Mainstream Compute

Analytics, inference, and specialised production workloads sometimes need more GPU flexibility than a standard rack server usually offers, but not a dedicated AI chassis. The DL385 Gen11 fits those environments where accelerator support adds value to a broad enterprise server role.

AMD Enterprise Standardisation

Many organisations standardise on one AMD-based 2U platform for virtualisation, databases, and mixed production services. The DL385 Gen11 is a practical fit where the goal is to cover a wider spread of enterprise workloads than the more narrowly efficient DL325.

Planning a DL385 Gen11 Deployment?

Our team can help design and deploy HPE ProLiant DL385 Gen11 infrastructure for virtualisation, software-defined compute, and storage-rich AMD enterprise environments.

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