The HPE ProLiant DL385 Gen11 Rack Server is a powerful 2U platform powered by AMD EPYC processors. Designed for virtualisation, AI, and data-intensive workloads, it delivers high core density, PCIe Gen5 expansion, and DDR5 memory for scalable enterprise infrastructure.
Guide price: £2,731.82 – £6,500.00Price range: £2,731.82 through £6,500.00 Ex. VAT
Virtualised environments and modern application platforms require compute infrastructure capable of delivering strong performance while maintaining efficiency and scalability.
The HPE ProLiant DL385 Gen11 is a dual-socket 2U rack server powered by 4th Generation AMD EPYC processors with high core density and support for large memory configurations. The platform supports DDR5 memory, PCIe Gen5 connectivity, and high-speed NVMe storage for demanding application workloads. Support for modern memory, storage, and I/O keeps application, database, and virtualisation workloads responsive as utilisation rises and data movement increases across the platform.
Extensive I/O expansion and storage flexibility allow the DL385 Gen11 to support workloads such as virtualisation, analytics, and large-scale data processing. High-density compute and platform bandwidth give infrastructure teams more room to consolidate services, standardise deployments, and avoid creating additional server silos as requirements grow. Organisations that require larger scale-up workloads than a 2-socket platform is designed for may also consider the HPE ProLiant DL560 Gen11 Mission-Critical Server, for supporting bigger memory footprints and consolidation ratios.
High core density and modern platform bandwidth enable organisations to consolidate workloads onto fewer servers while maintaining strong application performance.
Our specialists can help design and deploy HPE ProLiant DL385 Gen11 platforms aligned with virtualised and data-intensive infrastructure environments. It also gives IT teams a more practical platform for planned growth without adding unnecessary management overhead.
The HPE ProLiant Compute DL385 Gen11 is a 2U dual-socket AMD server designed for high-performance workloads, delivering scalable compute, large memory capacity, and flexible storage.
AMD EPYC Processor Platform
Supports dual AMD EPYC processors for compute-intensive workloads.
Large Memory Capacity
Supports high-capacity DDR5 memory for demanding applications.
Flexible Storage Options
Supports multiple drive configurations including NVMe.
PCIe Expansion
Enables high-speed connectivity for networking and storage.
HPE iLO Management
Provides remote management and monitoring.
Silicon Root of Trust
Ensures system security at the firmware level.
Automation and Monitoring
Supports HPE management platforms for operational control.
Whether supporting virtualisation or high-performance applications, we help design HPE ProLiant DL385 Gen11 environments for scalable compute performance.
Full specifications for this model are listed below.
| Product Family | HPE ProLiant |
|---|---|
| Product Series | DL385 |
| Platform Generation | |
| Deployment | Data Centre |
| Primary Use Case | High-Performance Compute |
| Product Tier | Standard |
| Chassis Type | |
| Form Factor | |
| CPU Vendor | |
| Processor Platform | |
| CPU Architecture Class | |
| Maximum CPUs Supported | |
| Memory Type | |
| Maximum Memory Capacity | |
| Memory Slots | |
| Maximum Memory Speed (MT/s) | |
| Drive Bay Configuration | |
| Maximum Storage Capacity | |
| NVMe Drive Support | |
| Maximum GPUs Supported | |
| PCI Express Slots | |
| PCIe Generation | |
| Embedded Network Ports | |
| Maximum Network Speed | |
| OCP / Network Expansion | |
| Maximum Power Supply (W) | |
| Power Redundancy | Hot-swappable PSUs |
| Remote Management |
Our specialists are here to help assess compatibility, compare suitable alternatives, or talk through your configuration needs before committing to a solution.
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The HPE ProLiant DL385 Gen11 Rack Server is designed for organisations that need a 2U dual-socket AMD platform for higher core density, larger memory scale, and broader expansion than a compact 1U host. It is best suited to workloads that need more storage and PCIe headroom than the DL325 Gen11, while remaining a mainstream enterprise server rather than moving into the specialised AI role of the DL380a family.
The DL385 Gen11 is a strong fit for larger virtualisation environments where host density, memory capacity, and local storage flexibility all matter at the same time. It works well where a 2U chassis gives more room for mixed VM growth than a smaller single-socket server.
Software-defined storage and compute platforms often need strong processor scale, fast PCIe Gen5 I/O, and flexible local media layouts in one chassis. The DL385 Gen11 suits these deployments because it combines dual-socket AMD performance with broader expansion than the DL325.
Application estates that need more local storage choice can use 8 SFF, 8 LFF, 12 EDSFF, or 48 SFF variants to match the workload. The DL385 Gen11 is well matched to environments where local media layout is part of the platform decision rather than a fixed compromise.
Analytics, inference, and specialised production workloads sometimes need more GPU flexibility than a standard rack server usually offers, but not a dedicated AI chassis. The DL385 Gen11 fits those environments where accelerator support adds value to a broad enterprise server role.
Many organisations standardise on one AMD-based 2U platform for virtualisation, databases, and mixed production services. The DL385 Gen11 is a practical fit where the goal is to cover a wider spread of enterprise workloads than the more narrowly efficient DL325.
Our team can help design and deploy HPE ProLiant DL385 Gen11 infrastructure for virtualisation, software-defined compute, and storage-rich AMD enterprise environments.
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Below you’ll find alternative models, suitable software and services that pair with this solution – helping you to avoid compatibility issues, reduce support overhead and deploy with confidence.
Not all deployments fit standard configurations. If you’re weighing up options or want a second opinion on your setup, our team is here to help with honest, straightforward advice backed by decades of vendor knowledge.




Not sure which model is right for your environment? Our specialists can help you select the right platform for your infrastructure requirements.