The HPE ProLiant DL380 Gen12 Rack Server is a next-generation 2U system for demanding workloads. Supporting next-gen Intel Xeon processors with DDR5 and PCIe Gen5, it delivers scalable compute, advanced security, and flexible infrastructure for modern data centres.
Guide price: Price range: £2,731.82 through £4,521.44 Ex. VAT
Modern data centres must support rapidly growing workloads while maintaining infrastructure efficiency, security, and long-term scalability.
The HPE ProLiant DL380 Gen12 delivers enterprise-class performance in a flexible 2U platform powered by Intel Xeon 6 processors. The system supports high-bandwidth DDR5 memory, PCIe Gen5 expansion, and high-speed NVMe storage to support demanding workloads including virtualisation, analytics, and AI-enabled applications. Support for modern memory, storage, and I/O keeps application, database, and virtualisation workloads responsive as utilisation rises and data movement increases across the platform.
High-speed I/O and storage connectivity allow networking, storage, and accelerator hardware to operate at full throughput, enabling the platform to support large-scale data processing and compute-intensive applications. High-density compute and platform bandwidth give infrastructure teams more room to consolidate services, standardise deployments, and avoid creating additional server silos as requirements grow. Organisations that require four-socket scale-up in a Gen12 platform may also consider the HPE ProLiant DL580 Gen12 Mission-Critical Server, for supporting larger consolidation and database estates with more CPU and memory headroom.
Improved processor efficiency and expanded platform bandwidth allow organisations to modernise data centre infrastructure while maintaining efficient rack utilisation and operational simplicity.
Our specialists can design and deploy HPE ProLiant DL380 Gen12 platforms aligned with modern enterprise workloads and long-term infrastructure growth.
The HPE ProLiant Compute DL380 Gen12 is a versatile 2U rack server designed for enterprise workloads, delivering a balance of performance, scalability, and security for virtualisation, hybrid cloud, and business-critical applications.
Intel Xeon 6 Processor Support
Supports next-generation Intel Xeon processors for improved compute performance and efficiency.
Flexible Memory Capacity
Supports DDR5 memory for high-speed data processing and application performance.
Scalable Storage Options
Supports SFF, LFF, and EDSFF drive configurations to meet diverse workload requirements.
PCIe Gen5 Expansion
Enables high-speed networking and storage expansion.
HPE iLO 7 Management
Provides secure remote management and server lifecycle control.
HPE Silicon Root of Trust
Delivers built-in security to protect firmware and system integrity.
HPE Compute Ops Management
Provides cloud-based management and visibility across distributed environments.
Whether supporting virtualisation, hybrid cloud, or enterprise applications, we help design HPE ProLiant DL380 Gen12 environments for performance, scalability, and security.
| Product Family | HPE ProLiant |
|---|---|
| Product Series | DL380 |
| Platform Generation | |
| Deployment | Data Centre |
| Primary Use Case | Enterprise Applications |
| Product Tier | Flagship |
| Chassis Type | |
| Form Factor | |
| CPU Vendor | |
| Processor Platform | |
| CPU Architecture Class | |
| Maximum CPUs Supported | |
| Memory Type | |
| Maximum Memory Capacity | |
| Memory Slots | |
| Maximum Memory Speed (MT/s) | |
| Drive Bay Configuration | |
| Maximum Storage Capacity | |
| NVMe Drive Support | |
| Maximum GPUs Supported | |
| PCI Express Slots | |
| PCIe Generation | |
| Embedded Network Ports | |
| Maximum Network Speed | |
| OCP / Network Expansion | |
| Maximum Power Supply (W) | |
| Power Redundancy | Hot-swappable PSUs |
| Remote Management |
The HPE ProLiant DL380 Gen12 Rack Server is designed for organisations that need a next-generation 2U dual-socket platform for demanding enterprise and hybrid cloud workloads. It is best suited to environments where higher Intel Xeon 6 core density, broader memory scale, and newer front-end storage options matter more than the earlier Gen11 platform or a more compact 1U server.
Hybrid cloud estates often need a stronger server baseline as virtualisation density, application demands, and data movement all increase together. The DL380 Gen12 fits these refresh projects where the goal is to modernise core infrastructure without moving away from a versatile 2U enterprise platform.
Business platforms with heavier data activity need a server that can combine processor scale with more advanced storage layouts. The DL380 Gen12 works well where 8 SFF, 24 SFF, 8 LFF, 12 LFF, or 12 EDSFF options are used to match application behaviour more closely than a one-layout server design allows.
Virtualisation environments replacing older 2U hosts often need a clearer gain in consolidation headroom rather than a simple like-for-like replacement. The DL380 Gen12 suits those deployments where more compute, memory, and faster front-end media need to come together in the same chassis.
Modern services increasingly benefit from faster local storage and denser front-end media choices. The DL380 Gen12 is a strong fit where EDSFF or NVMe-led designs support database, analytics, or infrastructure workloads that need more than conventional drive layouts.
For organisations standardising on a newer compute generation, the DL380 Gen12 provides a broader long-term platform than an entry or single-socket design. It is well matched to mainstream production estates that want one server family for evolving enterprise workloads.
Our team can help design and deploy HPE ProLiant DL380 Gen12 infrastructure for hybrid cloud, modern enterprise applications, and next-generation 2U compute environments.
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Below you’ll find alternative models, suitable software and services that pair with this solution – helping you to avoid compatibility issues, reduce support overhead and deploy with confidence.
Not all deployments fit standard configurations. If you’re weighing up options or want a second opinion on your setup, our team is here to help with honest, straightforward advice backed by decades of vendor knowledge.
Not sure which model is right for your environment? Our specialists can help you select the right platform for your infrastructure requirements.
